pre-mRNA 3' end processing protein WDR33 (WDR33)
Homo sapiens — UniProt Q9C0J8
Data last refreshed: (UniProt release unknown)
Key facts
pre-mRNA 3' end processing protein WDR33 (WDR33) is a protein from Homo sapiens identified by UniProt accession Q9C0J8, 1336 residues long. MolForge cross-references it against 0 known binders and 36 disease associations.
- UniProt accession: Q9C0J8; gene symbol WDR33.
- Organism: Homo sapiens.
- Length: 1336 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, neutrophil count and leukocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | pre-mRNA 3' end processing protein WDR33 |
|---|---|
| UniProt accession | Q9C0J8 |
| Gene | WDR33 |
| Organism | Homo sapiens |
| Length | 1336 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (36)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.51
- neutrophil count · score 0.21
- leukocyte count · score 0.17
- myeloid white cell count · score 0.10
- body mass index · score 0.07
- high density lipoprotein cholesterol measurement · score 0.07
- lymphocyte count · score 0.07
- apolipoprotein A 1 measurement · score 0.07
- hereditary persistence of fetal hemoglobin-sickle cell disease syndrome · score 0.05
- hemoglobin D disease · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9C0J8-F1 | alphafold | PREDICTED | 55.42 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9C0J8.
Amino-acid sequence (1336 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with WDR33?
The strongest Open Targets associations for WDR33 are neurodegenerative disease, neutrophil count, leukocyte count, myeloid white cell count and body mass index.
How long is the WDR33 protein?
The Homo sapiens WDR33 protein (UniProt Q9C0J8) is 1336 amino acids long.
Browse: Targets: W · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9C0J8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9C0J8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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