Class E basic helix-loop-helix protein 41 (BHLHE41)
Homo sapiens — UniProt Q9C0J9
Data last refreshed: (UniProt release unknown)
Key facts
Class E basic helix-loop-helix protein 41 (BHLHE41) is a protein from Homo sapiens identified by UniProt accession Q9C0J9, 482 residues long. MolForge cross-references it against 0 known binders and 221 disease associations.
- UniProt accession: Q9C0J9; gene symbol BHLHE41.
- Organism: Homo sapiens.
- Length: 482 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, platelet count and platelet crit.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Class E basic helix-loop-helix protein 41 |
|---|---|
| UniProt accession | Q9C0J9 |
| Gene | BHLHE41 |
| Organism | Homo sapiens |
| Length | 482 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (221)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.33
- platelet count · score 0.30
- platelet crit · score 0.28
- serum albumin measurement · score 0.25
- diabetes mellitus · score 0.24
- endocrine system disease · score 0.24
- lymphocyte count · score 0.21
- hair shape measurement · score 0.20
- leukocyte count · score 0.20
- heel bone mineral density · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9C0J9-F1 | alphafold | PREDICTED | 55.09 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9C0J9.
Amino-acid sequence (482 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BHLHE41?
The strongest Open Targets associations for BHLHE41 are neurodegenerative disease, platelet count, platelet crit, serum albumin measurement and diabetes mellitus.
How long is the BHLHE41 protein?
The Homo sapiens BHLHE41 protein (UniProt Q9C0J9) is 482 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9C0J9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9C0J9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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