Actin-related protein 3C (ACTR3C)
Homo sapiens — UniProt Q9C0K3
Data last refreshed: (UniProt release unknown)
Key facts
Actin-related protein 3C (ACTR3C) is a protein from Homo sapiens identified by UniProt accession Q9C0K3, 210 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.
- UniProt accession: Q9C0K3; gene symbol ACTR3C.
- Organism: Homo sapiens.
- Length: 210 amino acids.
- Top disease associations (Open Targets): appendicular lean mass, neurodegenerative disease and chemerin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Actin-related protein 3C |
|---|---|
| UniProt accession | Q9C0K3 |
| Gene | ACTR3C |
| Organism | Homo sapiens |
| Length | 210 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (22)
Diseases linked to this target (Open Targets).
- appendicular lean mass · score 0.31
- neurodegenerative disease · score 0.26
- chemerin measurement · score 0.21
- visual perception measurement · score 0.20
- platelet count · score 0.19
- blood protein measurement · score 0.11
- protein measurement · score 0.07
- self reported educational attainment · score 0.07
- adolescent idiopathic scoliosis · score 0.06
- retinoic acid receptor responder protein 2 measurement · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9C0K3-F1 | alphafold | PREDICTED | 87.37 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9C0K3.
Amino-acid sequence (210 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ACTR3C?
The strongest Open Targets associations for ACTR3C are appendicular lean mass, neurodegenerative disease, chemerin measurement, visual perception measurement and platelet count.
How long is the ACTR3C protein?
The Homo sapiens ACTR3C protein (UniProt Q9C0K3) is 210 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9C0K3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9C0K3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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