Olfactory receptor 2B2 (OR2B2)
Homo sapiens — UniProt Q9GZK3
Data last refreshed: (UniProt release unknown)
Key facts
Olfactory receptor 2B2 (OR2B2) is a protein from Homo sapiens identified by UniProt accession Q9GZK3, 357 residues long. MolForge cross-references it against 0 known binders and 74 disease associations.
- UniProt accession: Q9GZK3; gene symbol OR2B2.
- Organism: Homo sapiens.
- Length: 357 amino acids.
- Top disease associations (Open Targets): clear cell renal carcinoma, chronic lymphocytic leukemia and breast adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Olfactory receptor 2B2 |
|---|---|
| UniProt accession | Q9GZK3 |
| Gene | OR2B2 |
| Organism | Homo sapiens |
| Length | 357 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (74)
Diseases linked to this target (Open Targets).
- clear cell renal carcinoma · score 0.18
- chronic lymphocytic leukemia · score 0.18
- breast adenocarcinoma · score 0.18
- monocyte count · score 0.13
- schizophrenia · score 0.12
- bipolar disorder · score 0.11
- cognitive function measurement · score 0.11
- self reported educational attainment · score 0.11
- forced expiratory volume · score 0.11
- eosinophil count · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9GZK3-F1 | alphafold | PREDICTED | 79.84 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9GZK3.
Amino-acid sequence (357 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OR2B2?
The strongest Open Targets associations for OR2B2 are clear cell renal carcinoma, chronic lymphocytic leukemia, breast adenocarcinoma, monocyte count and schizophrenia.
How long is the OR2B2 protein?
The Homo sapiens OR2B2 protein (UniProt Q9GZK3) is 357 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9GZK3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9GZK3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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