Olfactory receptor 8D2 (OR8D2)
Homo sapiens — UniProt Q9GZM6
Data last refreshed: (UniProt release unknown)
Key facts
Olfactory receptor 8D2 (OR8D2) is a protein from Homo sapiens identified by UniProt accession Q9GZM6, 311 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.
- UniProt accession: Q9GZM6; gene symbol OR8D2.
- Organism: Homo sapiens.
- Length: 311 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, neuroblastoma and clear cell renal carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Olfactory receptor 8D2 |
|---|---|
| UniProt accession | Q9GZM6 |
| Gene | OR8D2 |
| Organism | Homo sapiens |
| Length | 311 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (7)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.25
- neuroblastoma · score 0.21
- clear cell renal carcinoma · score 0.18
- chronic lymphocytic leukemia · score 0.18
- neurofibrillary tangles measurement · score 0.03
- myocardial infarction · score 0.01
- gastric carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9GZM6-F1 | alphafold | PREDICTED | 88.25 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9GZM6.
Amino-acid sequence (311 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OR8D2?
The strongest Open Targets associations for OR8D2 are neurodegenerative disease, neuroblastoma, clear cell renal carcinoma, chronic lymphocytic leukemia and neurofibrillary tangles measurement.
How long is the OR8D2 protein?
The Homo sapiens OR8D2 protein (UniProt Q9GZM6) is 311 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9GZM6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9GZM6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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