Tubulointerstitial nephritis antigen-like (TINAGL1)
Homo sapiens — UniProt Q9GZM7
Data last refreshed: (UniProt release unknown)
Key facts
Tubulointerstitial nephritis antigen-like (TINAGL1) is a protein from Homo sapiens identified by UniProt accession Q9GZM7, 467 residues long. MolForge cross-references it against 0 known binders and 42 disease associations.
- UniProt accession: Q9GZM7; gene symbol TINAGL1.
- Organism: Homo sapiens.
- Length: 467 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, hepatocellular carcinoma and smoking status measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tubulointerstitial nephritis antigen-like |
|---|---|
| UniProt accession | Q9GZM7 |
| Gene | TINAGL1 |
| Organism | Homo sapiens |
| Length | 467 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (42)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.33
- hepatocellular carcinoma · score 0.08
- smoking status measurement · score 0.07
- systolic blood pressure · score 0.07
- neoplasm · score 0.06
- cancer · score 0.04
- appendicular lean mass · score 0.04
- gonorrhea · score 0.03
- triple-negative breast cancer · score 0.01
- squamous cell carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9GZM7-F1 | alphafold | PREDICTED | 86.21 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9GZM7.
Amino-acid sequence (467 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TINAGL1?
The strongest Open Targets associations for TINAGL1 are neurodegenerative disease, hepatocellular carcinoma, smoking status measurement, systolic blood pressure and neoplasm.
How long is the TINAGL1 protein?
The Homo sapiens TINAGL1 protein (UniProt Q9GZM7) is 467 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9GZM7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9GZM7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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