Actin-related protein 6 (ACTR6)
Homo sapiens — UniProt Q9GZN1
Data last refreshed: (UniProt release unknown)
Key facts
Actin-related protein 6 (ACTR6) is a protein from Homo sapiens identified by UniProt accession Q9GZN1, 396 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.
- UniProt accession: Q9GZN1; gene symbol ACTR6.
- Organism: Homo sapiens.
- Length: 396 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, adolescent idiopathic scoliosis and cardiovascular disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Actin-related protein 6 |
|---|---|
| UniProt accession | Q9GZN1 |
| Gene | ACTR6 |
| Organism | Homo sapiens |
| Length | 396 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (20)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.48
- adolescent idiopathic scoliosis · score 0.23
- cardiovascular disease · score 0.06
- gut microbiome measurement · score 0.03
- breast cancer · score 0.01
- chronic obstructive pulmonary disease · score 0.01
- Abnormal sperm morphology · score 0.01
- lung carcinoma · score 0.01
- Huntington disease · score 0.01
- colorectal cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9GZN1-F1 | alphafold | PREDICTED | 94.31 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9GZN1.
Amino-acid sequence (396 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ACTR6?
The strongest Open Targets associations for ACTR6 are neurodegenerative disease, adolescent idiopathic scoliosis, cardiovascular disease, gut microbiome measurement and breast cancer.
How long is the ACTR6 protein?
The Homo sapiens ACTR6 protein (UniProt Q9GZN1) is 396 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9GZN1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9GZN1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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