Protein rogdi homolog (ROGDI)
Homo sapiens — UniProt Q9GZN7
Data last refreshed: (UniProt release unknown)
Key facts
Protein rogdi homolog (ROGDI) is a protein from Homo sapiens identified by UniProt accession Q9GZN7, 287 residues long. MolForge cross-references it against 0 known binders and 46 disease associations.
- UniProt accession: Q9GZN7; gene symbol ROGDI.
- Organism: Homo sapiens.
- Length: 287 amino acids.
- Top disease associations (Open Targets): amelocerebrohypohidrotic syndrome, Amelo-cerebro-hypohidrotic syndrome and genetic disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein rogdi homolog |
|---|---|
| UniProt accession | Q9GZN7 |
| Gene | ROGDI |
| Organism | Homo sapiens |
| Length | 287 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (46)
Diseases linked to this target (Open Targets).
- amelocerebrohypohidrotic syndrome · score 0.79
- Amelo-cerebro-hypohidrotic syndrome · score 0.77
- genetic disorder · score 0.19
- Seizure · score 0.15
- skin aging · score 0.09
- lean body mass · score 0.08
- body height · score 0.07
- fat body mass · score 0.07
- whole body water mass · score 0.05
- appendicular lean mass · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9GZN7-F1 | alphafold | PREDICTED | 89.29 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9GZN7.
Amino-acid sequence (287 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ROGDI?
The strongest Open Targets associations for ROGDI are amelocerebrohypohidrotic syndrome, Amelo-cerebro-hypohidrotic syndrome, genetic disorder, Seizure and skin aging.
How long is the ROGDI protein?
The Homo sapiens ROGDI protein (UniProt Q9GZN7) is 287 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9GZN7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9GZN7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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