Adipose-secreted signaling protein (ADISSP)
Homo sapiens — UniProt Q9GZN8
Data last refreshed: (UniProt release unknown)
Key facts
Adipose-secreted signaling protein (ADISSP) is a protein from Homo sapiens identified by UniProt accession Q9GZN8, 174 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.
- UniProt accession: Q9GZN8; gene symbol ADISSP.
- Organism: Homo sapiens.
- Length: 174 amino acids.
- Top disease associations (Open Targets): mean corpuscular volume, mean reticulocyte volume and neutrophil count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Adipose-secreted signaling protein |
|---|---|
| UniProt accession | Q9GZN8 |
| Gene | ADISSP |
| Organism | Homo sapiens |
| Length | 174 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (20)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.32
- mean reticulocyte volume · score 0.21
- neutrophil count · score 0.16
- erythrocyte count · score 0.14
- red blood cell density measurement · score 0.12
- mean corpuscular hemoglobin concentration · score 0.12
- neutrophil percentage of leukocytes · score 0.10
- platelet component distribution width · score 0.09
- lymphocyte percentage of leukocytes · score 0.04
- appendicular lean mass · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9GZN8-F1 | alphafold | PREDICTED | 80.13 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9GZN8.
Amino-acid sequence (174 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ADISSP?
The strongest Open Targets associations for ADISSP are mean corpuscular volume, mean reticulocyte volume, neutrophil count, erythrocyte count and red blood cell density measurement.
How long is the ADISSP protein?
The Homo sapiens ADISSP protein (UniProt Q9GZN8) is 174 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9GZN8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9GZN8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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