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Neuromedin-U receptor 2 (NMUR2)

Homo sapiens — UniProt Q9GZQ4

Gene: NMUR2Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Neuromedin-U receptor 2 (NMUR2) is a protein from Homo sapiens identified by UniProt accession Q9GZQ4, 415 residues long. MolForge cross-references it against 2 known binders and 73 disease associations.

  • UniProt accession: Q9GZQ4; gene symbol NMUR2.
  • Organism: Homo sapiens.
  • Length: 415 amino acids.
  • Top disease associations (Open Targets): loneliness measurement, physical activity measurement and chronotype measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameNeuromedin-U receptor 2
UniProt accessionQ9GZQ4
GeneNMUR2
OrganismHomo sapiens
Length415 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (73)

Diseases linked to this target (Open Targets).

  • loneliness measurement · score 0.37
  • physical activity measurement · score 0.36
  • chronotype measurement · score 0.35
  • self reported educational attainment · score 0.35
  • schizophrenia · score 0.35
  • mathematical ability · score 0.33
  • migraine disorder · score 0.33
  • tea consumption measurement · score 0.32
  • attention deficit hyperactivity disorder · score 0.28
  • glioblastoma multiforme · score 0.27

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9GZQ4-F1alphafoldPREDICTED80.00—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9GZQ4.

Amino-acid sequence (415 residues)

MSGMEKLQNA SWIYQQKLED PFQKHLNSTE EYLAFLCGPR RSHFFLPVSV VYVPIFVVGV IGNVLVCLVI LQHQAMKTPT NYYLFSLAVS DLLVLLLGMP LEVYEMWRNY PFLFGPVGCY FKTALFETVC FASILSITTV SVERYVAILH PFRAKLQSTR RRALRILGIV WGFSVLFSLP NTSIHGIKFH YFPNGSLVPG SATCTVIKPM WIYNFIIQVT SFLFYLLPMT VISVLYYLMA LRLKKDKSLE ADEGNANIQR PCRKSVNKML FVLVLVFAIC WAPFHIDRLF FSFVEEWSES LAAVFNLVHV VSGVFFYLSS AVNPIIYNLL SRRFQAAFQN VISSFHKQWH SQHDPQLPPA QRNIFLTECH FVELTEDIGP QFPCQSSMHN SHLPAALSSE QMSRTNYQSF HFNKT

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with NMUR2?

The strongest Open Targets associations for NMUR2 are loneliness measurement, physical activity measurement, chronotype measurement, self reported educational attainment and schizophrenia.

How long is the NMUR2 protein?

The Homo sapiens NMUR2 protein (UniProt Q9GZQ4) is 415 amino acids long.

Browse: Targets: N · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9GZQ4
GeneNMUR2
OrganismHomo sapiens
Length415
Binders2
Diseases73
View on UniProt