ATP-dependent RNA helicase DDX24 (DDX24)
Homo sapiens — UniProt Q9GZR7
Data last refreshed: (UniProt release unknown)
Key facts
ATP-dependent RNA helicase DDX24 (DDX24) is a protein from Homo sapiens identified by UniProt accession Q9GZR7, 859 residues long. MolForge cross-references it against 0 known binders and 42 disease associations.
- UniProt accession: Q9GZR7; gene symbol DDX24.
- Organism: Homo sapiens.
- Length: 859 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, hepatocellular carcinoma and non-small cell lung carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | ATP-dependent RNA helicase DDX24 |
|---|---|
| UniProt accession | Q9GZR7 |
| Gene | DDX24 |
| Organism | Homo sapiens |
| Length | 859 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (42)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.41
- hepatocellular carcinoma · score 0.08
- non-small cell lung carcinoma · score 0.07
- neoplasm · score 0.05
- congenital lipoid adrenal hyperplasia due to STAR deficency · score 0.03
- 46,XX ovotesticular disorder of sex development · score 0.03
- congenital adrenal hyperplasia due to cytochrome P450 oxidoreductase deficiency · score 0.03
- Mayer-Rokitansky-Kuster-Hauser syndrome · score 0.03
- mucocutaneous lymph node syndrome · score 0.03
- cancer · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9GZR7-F1 | alphafold | PREDICTED | 64.60 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9GZR7.
Amino-acid sequence (859 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DDX24?
The strongest Open Targets associations for DDX24 are neurodegenerative disease, hepatocellular carcinoma, non-small cell lung carcinoma, neoplasm and congenital lipoid adrenal hyperplasia due to STAR deficency.
How long is the DDX24 protein?
The Homo sapiens DDX24 protein (UniProt Q9GZR7) is 859 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9GZR7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9GZR7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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