Superkiller complex protein 8 (SKIC8)
Homo sapiens — UniProt Q9GZS3
Data last refreshed: (UniProt release unknown)
Key facts
Superkiller complex protein 8 (SKIC8) is a protein from Homo sapiens identified by UniProt accession Q9GZS3, 305 residues long. MolForge cross-references it against 0 known binders and 34 disease associations.
- UniProt accession: Q9GZS3; gene symbol SKIC8.
- Organism: Homo sapiens.
- Length: 305 amino acids.
- Top disease associations (Open Targets): Red cell distribution width, mathematical ability and hemoglobin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Superkiller complex protein 8 |
|---|---|
| UniProt accession | Q9GZS3 |
| Gene | SKIC8 |
| Organism | Homo sapiens |
| Length | 305 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (34)
Diseases linked to this target (Open Targets).
- Red cell distribution width · score 0.28
- mathematical ability · score 0.21
- hemoglobin measurement · score 0.19
- cognitive function measurement · score 0.19
- mean corpuscular hemoglobin · score 0.18
- HbA1c measurement · score 0.15
- reticulocyte count · score 0.10
- platelet count · score 0.10
- platelet crit · score 0.08
- neurofibrillary tangles measurement · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9GZS3-F1 | alphafold | PREDICTED | 96.44 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9GZS3.
Amino-acid sequence (305 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SKIC8?
The strongest Open Targets associations for SKIC8 are Red cell distribution width, mathematical ability, hemoglobin measurement, cognitive function measurement and mean corpuscular hemoglobin.
How long is the SKIC8 protein?
The Homo sapiens SKIC8 protein (UniProt Q9GZS3) is 305 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9GZS3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9GZS3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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