Carbohydrate sulfotransferase 5 (CHST5)
Homo sapiens — UniProt Q9GZS9
Data last refreshed: (UniProt release unknown)
Key facts
Carbohydrate sulfotransferase 5 (CHST5) is a protein from Homo sapiens identified by UniProt accession Q9GZS9, 411 residues long. MolForge cross-references it against 0 known binders and 95 disease associations.
- UniProt accession: Q9GZS9; gene symbol CHST5.
- Organism: Homo sapiens.
- Length: 411 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, blood protein measurement and metabolite measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Carbohydrate sulfotransferase 5 |
|---|---|
| UniProt accession | Q9GZS9 |
| Gene | CHST5 |
| Organism | Homo sapiens |
| Length | 411 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (95)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.26
- blood protein measurement · score 0.17
- metabolite measurement · score 0.10
- Increased circulating prolactin concentration · score 0.09
- hyperprolactinemia · score 0.09
- Fuchs endothelial corneal dystrophy · score 0.08
- X-linked endothelial corneal dystrophy · score 0.07
- X-linked corneal dermoid · score 0.07
- lattice corneal dystrophy type I · score 0.07
- Lisch epithelial corneal dystrophy · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9GZS9-F1 | alphafold | PREDICTED | 88.22 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9GZS9.
Amino-acid sequence (411 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CHST5?
The strongest Open Targets associations for CHST5 are neurodegenerative disease, blood protein measurement, metabolite measurement, Increased circulating prolactin concentration and hyperprolactinemia.
How long is the CHST5 protein?
The Homo sapiens CHST5 protein (UniProt Q9GZS9) is 411 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9GZS9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9GZS9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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