Serine racemase (SRR)
Homo sapiens — UniProt Q9GZT4
Data last refreshed: (UniProt release unknown)
Key facts
Serine racemase (SRR) is a protein from Homo sapiens identified by UniProt accession Q9GZT4, 340 residues long. MolForge cross-references it against 0 known binders and 155 disease associations.
- UniProt accession: Q9GZT4; gene symbol SRR.
- Organism: Homo sapiens.
- Length: 340 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, Parkinson disease and Alzheimer disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Serine racemase |
|---|---|
| UniProt accession | Q9GZT4 |
| Gene | SRR |
| Organism | Homo sapiens |
| Length | 340 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (155)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.49
- Parkinson disease · score 0.29
- Alzheimer disease · score 0.29
- lysosomal storage disease · score 0.29
- multiple sclerosis · score 0.29
- sex hormone-binding globulin measurement · score 0.20
- lean body mass · score 0.19
- mean corpuscular volume · score 0.19
- mean corpuscular hemoglobin concentration · score 0.14
- cortical surface area measurement · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9GZT4-F1 | alphafold | PREDICTED | 93.92 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9GZT4.
Amino-acid sequence (340 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SRR?
The strongest Open Targets associations for SRR are neurodegenerative disease, Parkinson disease, Alzheimer disease, lysosomal storage disease and multiple sclerosis.
How long is the SRR protein?
The Homo sapiens SRR protein (UniProt Q9GZT4) is 340 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9GZT4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9GZT4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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