Protein Wnt-10a (WNT10A)
Homo sapiens — UniProt Q9GZT5
Data last refreshed: (UniProt release unknown)
Key facts
Protein Wnt-10a (WNT10A) is a protein from Homo sapiens identified by UniProt accession Q9GZT5, 417 residues long. MolForge cross-references it against 0 known binders and 413 disease associations.
- UniProt accession: Q9GZT5; gene symbol WNT10A.
- Organism: Homo sapiens.
- Length: 417 amino acids.
- Top disease associations (Open Targets): tooth agenesis, selective, 4, odonto-onycho-dermal dysplasia and Schöpf-Schulz-Passarge syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein Wnt-10a |
|---|---|
| UniProt accession | Q9GZT5 |
| Gene | WNT10A |
| Organism | Homo sapiens |
| Length | 417 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (413)
Diseases linked to this target (Open Targets).
- tooth agenesis, selective, 4 · score 0.80
- odonto-onycho-dermal dysplasia · score 0.78
- Schöpf-Schulz-Passarge syndrome · score 0.74
- SchC6pf-Schulz-Passarge syndrome · score 0.67
- tooth agenesis · score 0.60
- genetic disorder · score 0.50
- tooth agenesis, selective, 2 · score 0.43
- refractive error measurement · score 0.41
- autosomal recessive hypohidrotic ectodermal dysplasia · score 0.38
- hair shape measurement · score 0.38
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9GZT5-F1 | alphafold | PREDICTED | 81.89 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9GZT5.
Amino-acid sequence (417 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with WNT10A?
The strongest Open Targets associations for WNT10A are tooth agenesis, selective, 4, odonto-onycho-dermal dysplasia, Schöpf-Schulz-Passarge syndrome, SchC6pf-Schulz-Passarge syndrome and tooth agenesis.
How long is the WNT10A protein?
The Homo sapiens WNT10A protein (UniProt Q9GZT5) is 417 amino acids long.
Browse: Targets: W · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9GZT5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9GZT5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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