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Coiled-coil domain-containing protein 90B, mitochondrial (CCDC90B)

Homo sapiens — UniProt Q9GZT6

Gene: CCDC90BHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Coiled-coil domain-containing protein 90B, mitochondrial (CCDC90B) is a protein from Homo sapiens identified by UniProt accession Q9GZT6, 254 residues long. MolForge cross-references it against 0 known binders and 27 disease associations.

  • UniProt accession: Q9GZT6; gene symbol CCDC90B.
  • Organism: Homo sapiens.
  • Length: 254 amino acids.
  • Top disease associations (Open Targets): chronotype measurement, hypertension and schizophrenia.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameCoiled-coil domain-containing protein 90B, mitochondrial
UniProt accessionQ9GZT6
GeneCCDC90B
OrganismHomo sapiens
Length254 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (27)

Diseases linked to this target (Open Targets).

  • chronotype measurement · score 0.27
  • hypertension · score 0.15
  • schizophrenia · score 0.09
  • diet measurement · score 0.09
  • anorexia nervosa · score 0.08
  • Parkinson disease · score 0.07
  • health study participation · score 0.07
  • putamen volume · score 0.06
  • brain volume measurement · score 0.06
  • neuroimaging measurement · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9GZT6-F1alphafoldPREDICTED81.97—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9GZT6.

Amino-acid sequence (254 residues)

MNSRQAWRLF LSQGRGDRWV SRPRGHFSPA LRREFFTTTT KEGYDRRPVD ITPLEQRKLT FDTHALVQDL ETHGFDKTQA ETIVSALTAL SNVSLDTIYK EMVTQAQQEI TVQQLMAHLD AIRKDMVILE KSEFANLRAE NEKMKIELDQ VKQQLMHETS RIRADNKLDI NLERSRVTDM FTDQEKQLME TTTEFTKKDT QTKSIISETS NKIDAEIASL KTLMESNKLE TIRYLAASVF TCLAIALGFY RFWK

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with CCDC90B?

The strongest Open Targets associations for CCDC90B are chronotype measurement, hypertension, schizophrenia, diet measurement and anorexia nervosa.

How long is the CCDC90B protein?

The Homo sapiens CCDC90B protein (UniProt Q9GZT6) is 254 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9GZT6
GeneCCDC90B
OrganismHomo sapiens
Length254
Binders0
Diseases27
View on UniProt