NIF3-like protein 1 (NIF3L1)
Homo sapiens — UniProt Q9GZT8
Data last refreshed: (UniProt release unknown)
Key facts
NIF3-like protein 1 (NIF3L1) is a protein from Homo sapiens identified by UniProt accession Q9GZT8, 377 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.
- UniProt accession: Q9GZT8; gene symbol NIF3L1.
- Organism: Homo sapiens.
- Length: 377 amino acids.
- Top disease associations (Open Targets): body height, total blood protein measurement and monocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | NIF3-like protein 1 |
|---|---|
| UniProt accession | Q9GZT8 |
| Gene | NIF3L1 |
| Organism | Homo sapiens |
| Length | 377 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (19)
Diseases linked to this target (Open Targets).
- body height · score 0.06
- total blood protein measurement · score 0.04
- monocyte count · score 0.03
- mean platelet volume · score 0.03
- red blood cell density measurement · score 0.02
- appendicular lean mass · score 0.02
- juvenile amyotrophic lateral sclerosis · score 0.01
- amyotrophic lateral sclerosis type 2, juvenile · score 0.01
- Alzheimer disease · score 0.01
- nervous system disease · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9GZT8-F1 | alphafold | PREDICTED | 91.75 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9GZT8.
Amino-acid sequence (377 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NIF3L1?
The strongest Open Targets associations for NIF3L1 are body height, total blood protein measurement, monocyte count, mean platelet volume and red blood cell density measurement.
How long is the NIF3L1 protein?
The Homo sapiens NIF3L1 protein (UniProt Q9GZT8) is 377 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9GZT8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9GZT8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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