Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (CTDSP1)
Homo sapiens — UniProt Q9GZU7
Data last refreshed: (UniProt release unknown)
Key facts
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (CTDSP1) is a protein from Homo sapiens identified by UniProt accession Q9GZU7, 261 residues long. MolForge cross-references it against 0 known binders and 40 disease associations.
- UniProt accession: Q9GZU7; gene symbol CTDSP1.
- Organism: Homo sapiens.
- Length: 261 amino acids.
- Top disease associations (Open Targets): multiple sclerosis, Alzheimer disease and lysosomal storage disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 |
|---|---|
| UniProt accession | Q9GZU7 |
| Gene | CTDSP1 |
| Organism | Homo sapiens |
| Length | 261 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (40)
Diseases linked to this target (Open Targets).
- multiple sclerosis · score 0.36
- Alzheimer disease · score 0.36
- lysosomal storage disease · score 0.36
- Parkinson disease · score 0.36
- neurodegenerative disease · score 0.36
- neuroinflammatory disorder · score 0.26
- mean corpuscular hemoglobin concentration · score 0.21
- reticulocyte measurement · score 0.15
- Immature Reticulocyte Fraction Measurement · score 0.05
- platelet count · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9GZU7-F1 | alphafold | PREDICTED | 81.02 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9GZU7.
Amino-acid sequence (261 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CTDSP1?
The strongest Open Targets associations for CTDSP1 are multiple sclerosis, Alzheimer disease, lysosomal storage disease, Parkinson disease and neurodegenerative disease.
How long is the CTDSP1 protein?
The Homo sapiens CTDSP1 protein (UniProt Q9GZU7) is 261 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9GZU7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9GZU7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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