Ankyrin repeat domain-containing protein 2 (ANKRD2)
Homo sapiens — UniProt Q9GZV1
Data last refreshed: (UniProt release unknown)
Key facts
Ankyrin repeat domain-containing protein 2 (ANKRD2) is a protein from Homo sapiens identified by UniProt accession Q9GZV1, 360 residues long. MolForge cross-references it against 0 known binders and 51 disease associations.
- UniProt accession: Q9GZV1; gene symbol ANKRD2.
- Organism: Homo sapiens.
- Length: 360 amino acids.
- Top disease associations (Open Targets): oral squamous cell carcinoma, osteosarcoma and head and neck squamous cell carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ankyrin repeat domain-containing protein 2 |
|---|---|
| UniProt accession | Q9GZV1 |
| Gene | ANKRD2 |
| Organism | Homo sapiens |
| Length | 360 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (51)
Diseases linked to this target (Open Targets).
- oral squamous cell carcinoma · score 0.07
- osteosarcoma · score 0.07
- head and neck squamous cell carcinoma · score 0.05
- cancer · score 0.04
- neoplasm · score 0.03
- hypertrophic cardiomyopathy · score 0.03
- amino acid measurement · score 0.02
- protein measurement · score 0.02
- blood metabolite measurement · score 0.02
- congenital myopathy · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9GZV1-F1 | alphafold | PREDICTED | 76.80 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9GZV1.
Amino-acid sequence (360 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ANKRD2?
The strongest Open Targets associations for ANKRD2 are oral squamous cell carcinoma, osteosarcoma, head and neck squamous cell carcinoma, cancer and neoplasm.
How long is the ANKRD2 protein?
The Homo sapiens ANKRD2 protein (UniProt Q9GZV1) is 360 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9GZV1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9GZV1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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