PR domain zinc finger protein 14 (PRDM14)
Homo sapiens — UniProt Q9GZV8
Data last refreshed: (UniProt release unknown)
Key facts
PR domain zinc finger protein 14 (PRDM14) is a protein from Homo sapiens identified by UniProt accession Q9GZV8, 571 residues long. MolForge cross-references it against 0 known binders and 170 disease associations.
- UniProt accession: Q9GZV8; gene symbol PRDM14.
- Organism: Homo sapiens.
- Length: 571 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, testicular carcinoma and Testicular Germ Cell Tumor.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | PR domain zinc finger protein 14 |
|---|---|
| UniProt accession | Q9GZV8 |
| Gene | PRDM14 |
| Organism | Homo sapiens |
| Length | 571 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (170)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- testicular carcinoma · score 0.32
- Testicular Germ Cell Tumor · score 0.32
- visual perception measurement · score 0.28
- schizophrenia · score 0.20
- cystatin C measurement · score 0.12
- lymphocyte count · score 0.11
- neoplasm · score 0.09
- cancer · score 0.09
- azoospermia · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9GZV8-F1 | alphafold | PREDICTED | 59.90 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9GZV8.
Amino-acid sequence (571 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PRDM14?
The strongest Open Targets associations for PRDM14 are neurodegenerative disease, testicular carcinoma, Testicular Germ Cell Tumor, visual perception measurement and schizophrenia.
How long is the PRDM14 protein?
The Homo sapiens PRDM14 protein (UniProt Q9GZV8) is 571 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9GZV8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9GZV8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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