Membrane-spanning 4-domains subfamily A member 7 (MS4A7)
Homo sapiens — UniProt Q9GZW8
Data last refreshed: (UniProt release unknown)
Key facts
Membrane-spanning 4-domains subfamily A member 7 (MS4A7) is a protein from Homo sapiens identified by UniProt accession Q9GZW8, 240 residues long. MolForge cross-references it against 0 known binders and 27 disease associations.
- UniProt accession: Q9GZW8; gene symbol MS4A7.
- Organism: Homo sapiens.
- Length: 240 amino acids.
- Top disease associations (Open Targets): monocyte count, ferritin measurement and HbA1c measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Membrane-spanning 4-domains subfamily A member 7 |
|---|---|
| UniProt accession | Q9GZW8 |
| Gene | MS4A7 |
| Organism | Homo sapiens |
| Length | 240 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (27)
Diseases linked to this target (Open Targets).
- monocyte count · score 0.27
- ferritin measurement · score 0.17
- HbA1c measurement · score 0.17
- platelet count · score 0.13
- blood protein measurement · score 0.10
- monocyte percentage of leukocytes · score 0.09
- cystatin C measurement · score 0.07
- neutrophil percentage of leukocytes · score 0.04
- macrophage activation syndrome · score 0.04
- X-linked lymphoproliferative disease · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9GZW8-F1 | alphafold | PREDICTED | 75.52 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9GZW8.
Amino-acid sequence (240 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MS4A7?
The strongest Open Targets associations for MS4A7 are monocyte count, ferritin measurement, HbA1c measurement, platelet count and blood protein measurement.
How long is the MS4A7 protein?
The Homo sapiens MS4A7 protein (UniProt Q9GZW8) is 240 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9GZW8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9GZW8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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