Prostate and breast cancer overexpressed gene 1 protein (PBOV1)
Homo sapiens — UniProt Q9GZY1
Data last refreshed: (UniProt release unknown)
Key facts
Prostate and breast cancer overexpressed gene 1 protein (PBOV1) is a protein from Homo sapiens identified by UniProt accession Q9GZY1, 135 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.
- UniProt accession: Q9GZY1; gene symbol PBOV1.
- Organism: Homo sapiens.
- Length: 135 amino acids.
- Top disease associations (Open Targets): hepatocellular carcinoma, cancer and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Prostate and breast cancer overexpressed gene 1 protein |
|---|---|
| UniProt accession | Q9GZY1 |
| Gene | PBOV1 |
| Organism | Homo sapiens |
| Length | 135 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (21)
Diseases linked to this target (Open Targets).
- hepatocellular carcinoma · score 0.10
- cancer · score 0.07
- neoplasm · score 0.07
- pachyonychia congenita · score 0.07
- sebaceous of Jadassohn nevus · score 0.05
- actinic keratosis · score 0.05
- squamous cell carcinoma · score 0.04
- Rheumatoid arthritis · score 0.04
- breast carcinoma · score 0.02
- phosphatidylcholine ether measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9GZY1-F1 | alphafold | PREDICTED | 51.89 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9GZY1.
Amino-acid sequence (135 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PBOV1?
The strongest Open Targets associations for PBOV1 are hepatocellular carcinoma, cancer, neoplasm, pachyonychia congenita and sebaceous of Jadassohn nevus.
How long is the PBOV1 protein?
The Homo sapiens PBOV1 protein (UniProt Q9GZY1) is 135 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9GZY1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9GZY1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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