Disintegrin and metalloproteinase domain-containing protein 19 (ADAM19)
Homo sapiens — UniProt Q9H013
Data last refreshed: (UniProt release unknown)
Key facts
Disintegrin and metalloproteinase domain-containing protein 19 (ADAM19) is a protein from Homo sapiens identified by UniProt accession Q9H013, 955 residues long. MolForge cross-references it against 0 known binders and 236 disease associations.
- UniProt accession: Q9H013; gene symbol ADAM19.
- Organism: Homo sapiens.
- Length: 955 amino acids.
- Top disease associations (Open Targets): chronic obstructive pulmonary disease, FEV/FVC ratio and mean platelet volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Disintegrin and metalloproteinase domain-containing protein 19 |
|---|---|
| UniProt accession | Q9H013 |
| Gene | ADAM19 |
| Organism | Homo sapiens |
| Length | 955 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (236)
Diseases linked to this target (Open Targets).
- chronic obstructive pulmonary disease · score 0.48
- FEV/FVC ratio · score 0.47
- mean platelet volume · score 0.42
- forced expiratory volume · score 0.41
- smoking status measurement · score 0.39
- blood protein measurement · score 0.39
- pulmonary function measurement · score 0.38
- peak expiratory flow · score 0.38
- asthma · score 0.33
- Inhalant adrenergic use measurement · score 0.33
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H013-F1 | alphafold | PREDICTED | 69.94 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H013.
Amino-acid sequence (955 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ADAM19?
The strongest Open Targets associations for ADAM19 are chronic obstructive pulmonary disease, FEV/FVC ratio, mean platelet volume, forced expiratory volume and smoking status measurement.
How long is the ADAM19 protein?
The Homo sapiens ADAM19 protein (UniProt Q9H013) is 955 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H013 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H013 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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