Dynein regulatory complex subunit 3 (DRC3)
Homo sapiens — UniProt Q9H069
Data last refreshed: (UniProt release unknown)
Key facts
Dynein regulatory complex subunit 3 (DRC3) is a protein from Homo sapiens identified by UniProt accession Q9H069, 523 residues long. MolForge cross-references it against 0 known binders and 56 disease associations.
- UniProt accession: Q9H069; gene symbol DRC3.
- Organism: Homo sapiens.
- Length: 523 amino acids.
- Top disease associations (Open Targets): serum alanine aminotransferase measurement, schizophrenia and systolic blood pressure.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Dynein regulatory complex subunit 3 |
|---|---|
| UniProt accession | Q9H069 |
| Gene | DRC3 |
| Organism | Homo sapiens |
| Length | 523 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (56)
Diseases linked to this target (Open Targets).
- serum alanine aminotransferase measurement · score 0.29
- schizophrenia · score 0.25
- systolic blood pressure · score 0.24
- BMI-adjusted waist-hip ratio · score 0.22
- autism spectrum disorder · score 0.17
- attention deficit hyperactivity disorder · score 0.16
- bipolar disorder · score 0.15
- unipolar depression · score 0.15
- Tourette syndrome · score 0.15
- obsessive-compulsive disorder · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H069-F1 | alphafold | PREDICTED | 91.85 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H069.
Amino-acid sequence (523 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DRC3?
The strongest Open Targets associations for DRC3 are serum alanine aminotransferase measurement, schizophrenia, systolic blood pressure, BMI-adjusted waist-hip ratio and autism spectrum disorder.
How long is the DRC3 protein?
The Homo sapiens DRC3 protein (UniProt Q9H069) is 523 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H069 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H069 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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