Polyadenylate-binding protein-interacting protein 1 (PAIP1)
Homo sapiens — UniProt Q9H074
Data last refreshed: (UniProt release unknown)
Key facts
Polyadenylate-binding protein-interacting protein 1 (PAIP1) is a protein from Homo sapiens identified by UniProt accession Q9H074, 479 residues long. MolForge cross-references it against 0 known binders and 129 disease associations.
- UniProt accession: Q9H074; gene symbol PAIP1.
- Organism: Homo sapiens.
- Length: 479 amino acids.
- Top disease associations (Open Targets): Red cell distribution width, reticulocyte count and reticulocyte measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Polyadenylate-binding protein-interacting protein 1 |
|---|---|
| UniProt accession | Q9H074 |
| Gene | PAIP1 |
| Organism | Homo sapiens |
| Length | 479 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (129)
Diseases linked to this target (Open Targets).
- Red cell distribution width · score 0.21
- reticulocyte count · score 0.18
- reticulocyte measurement · score 0.17
- lymphocyte count · score 0.12
- self reported educational attainment · score 0.09
- forced expiratory volume · score 0.09
- calf circumference measurement · score 0.09
- leukocyte count · score 0.09
- Immature Reticulocyte Fraction Measurement · score 0.08
- red blood cell density measurement · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H074-F1 | alphafold | PREDICTED | 71.81 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H074.
Amino-acid sequence (479 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PAIP1?
The strongest Open Targets associations for PAIP1 are Red cell distribution width, reticulocyte count, reticulocyte measurement, lymphocyte count and self reported educational attainment.
How long is the PAIP1 protein?
The Homo sapiens PAIP1 protein (UniProt Q9H074) is 479 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H074 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H074 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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