Ras-related protein Rab-33B (RAB33B)
Homo sapiens — UniProt Q9H082
Data last refreshed: (UniProt release unknown)
Key facts
Ras-related protein Rab-33B (RAB33B) is a protein from Homo sapiens identified by UniProt accession Q9H082, 229 residues long. MolForge cross-references it against 0 known binders and 115 disease associations.
- UniProt accession: Q9H082; gene symbol RAB33B.
- Organism: Homo sapiens.
- Length: 229 amino acids.
- Top disease associations (Open Targets): Smith-McCort dysplasia, Skeletal dysplasia and genetic disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ras-related protein Rab-33B |
|---|---|
| UniProt accession | Q9H082 |
| Gene | RAB33B |
| Organism | Homo sapiens |
| Length | 229 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (115)
Diseases linked to this target (Open Targets).
- Smith-McCort dysplasia · score 0.71
- Skeletal dysplasia · score 0.34
- genetic disorder · score 0.18
- FEV/FVC ratio · score 0.12
- Familial progressive cardiac conduction defect · score 0.06
- Brugada syndrome · score 0.06
- Intermediate osteopetrosis · score 0.05
- gnathodiaphyseal dysplasia · score 0.05
- familial atrial fibrillation · score 0.05
- Metaphyseal chondrodysplasia, Schmid type · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H082-F1 | alphafold | PREDICTED | 80.65 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H082.
Amino-acid sequence (229 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RAB33B?
The strongest Open Targets associations for RAB33B are Smith-McCort dysplasia, Skeletal dysplasia, genetic disorder, FEV/FVC ratio and Familial progressive cardiac conduction defect.
How long is the RAB33B protein?
The Homo sapiens RAB33B protein (UniProt Q9H082) is 229 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H082 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H082 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.