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Zinc finger MYND domain-containing protein 15 (ZMYND15)

Homo sapiens — UniProt Q9H091

Gene: ZMYND15Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Zinc finger MYND domain-containing protein 15 (ZMYND15) is a protein from Homo sapiens identified by UniProt accession Q9H091, 742 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.

  • UniProt accession: Q9H091; gene symbol ZMYND15.
  • Organism: Homo sapiens.
  • Length: 742 amino acids.
  • Top disease associations (Open Targets): spermatogenic failure 14, male infertility with azoospermia or oligozoospermia due to single gene mutation and azoospermia.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameZinc finger MYND domain-containing protein 15
UniProt accessionQ9H091
GeneZMYND15
OrganismHomo sapiens
Length742 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (21)

Diseases linked to this target (Open Targets).

  • spermatogenic failure 14 · score 0.58
  • male infertility with azoospermia or oligozoospermia due to single gene mutation · score 0.37
  • azoospermia · score 0.35
  • lymphocyte count · score 0.12
  • male infertility · score 0.11
  • mean arterial pressure · score 0.07
  • blood protein measurement · score 0.04
  • leukocyte count · score 0.04
  • triglyceride measurement · score 0.04
  • diastolic blood pressure · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9H091-F1alphafoldPREDICTED72.04—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H091.

Amino-acid sequence (742 residues)

MEFVSGYRDE FLDFTALLFG WFRKFVAERG AVGTSLEGRC RQLEAQIRRL PQDPALWVLH VLPNHSVGIS LGQGAEPGPG PGLGTAWLLG DNPPLHLRDL SPYISFVSLE DGEEGEEEEE EDEEEEKRED GGAGSTEKVE PEEDRELAPT SRESPQETNP PGESEEAARE AGGGKDGCRE DRVENETRPQ KRKGQRSEAA PLHVSCLLLV TDEHGTILGI DLLVDGAQGT ASWGSGTKDL APWAYALLCH SMACPMGSGD PRKPRQLTVG DARLHRELES LVPRLGVKLA KTPMRTWGPR PGFTFASLRA RTCHVCHRHS FEAKLTPCPQ CSAVLYCGEA CLRADWQRCP DDVSHRFWCP RLAAFMERAG ELATLPFTYT AEVTSETFNK EAFLASRGLT RGYWTQLSML IPGPGFSRHP RGNTPSLSLL RGGDPYQLLQ GDGTALMPPV PPHPPRGVFG SWQDYYTWRG LSLDSPIAVL LTYPLTVYYV ITHLVPQSFP ELNIQNKQSL KIHVVEAGKE FDLVMVFWEL LVLLPHVALE LQFVGDGLPP ESDEQHFTLQ RDSLEVSVRP GSGISARPSS GTKEKGGRRD LQIKVSARPY HLFQGPKPDL VIGFNSGFAL KDTWLRSLPR LQSLRVPAFF TESSEYSCVM DGQTMAVATG GGTSPPQPNP FRSPFRLRAA DNCMSWYCNA FIFHLVYKPA QGSGARPAPG PPPPSPTPSA PPAPTRRRRG EKKPGRGARR RK

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with ZMYND15?

The strongest Open Targets associations for ZMYND15 are spermatogenic failure 14, male infertility with azoospermia or oligozoospermia due to single gene mutation, azoospermia, lymphocyte count and male infertility.

How long is the ZMYND15 protein?

The Homo sapiens ZMYND15 protein (UniProt Q9H091) is 742 amino acids long.

Browse: Targets: Z · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9H091
GeneZMYND15
OrganismHomo sapiens
Length742
Binders0
Diseases21
View on UniProt