Dynein regulatory complex protein 9 (DRC9)
Homo sapiens — UniProt Q9H095
Data last refreshed: (UniProt release unknown)
Key facts
Dynein regulatory complex protein 9 (DRC9) is a protein from Homo sapiens identified by UniProt accession Q9H095, 443 residues long. MolForge cross-references it against 0 known binders and 119 disease associations.
- UniProt accession: Q9H095; gene symbol DRC9.
- Organism: Homo sapiens.
- Length: 443 amino acids.
- Top disease associations (Open Targets): Blackfan-Diamond anemia, Diamond-Blackfan anemia and basophil count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Dynein regulatory complex protein 9 |
|---|---|
| UniProt accession | Q9H095 |
| Gene | DRC9 |
| Organism | Homo sapiens |
| Length | 443 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (119)
Diseases linked to this target (Open Targets).
- Blackfan-Diamond anemia · score 0.53
- Diamond-Blackfan anemia · score 0.46
- basophil count · score 0.20
- azoospermia · score 0.11
- male infertility with teratozoospermia due to single gene mutation · score 0.10
- spermatogenic failure 65 · score 0.10
- spermatogenic failure, X-linked, 3 · score 0.10
- spermatogenic failure 56 · score 0.10
- spermatogenic failure 59 · score 0.10
- spermatogenic failure 73 · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H095-F1 | alphafold | PREDICTED | 71.53 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H095.
Amino-acid sequence (443 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DRC9?
The strongest Open Targets associations for DRC9 are Blackfan-Diamond anemia, Diamond-Blackfan anemia, basophil count, azoospermia and male infertility with teratozoospermia due to single gene mutation.
How long is the DRC9 protein?
The Homo sapiens DRC9 protein (UniProt Q9H095) is 443 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H095 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H095 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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