RNA cytidine acetyltransferase (NAT10)
Homo sapiens — UniProt Q9H0A0
Data last refreshed: (UniProt release unknown)
Key facts
RNA cytidine acetyltransferase (NAT10) is a protein from Homo sapiens identified by UniProt accession Q9H0A0, 1025 residues long. MolForge cross-references it against 0 known binders and 159 disease associations.
- UniProt accession: Q9H0A0; gene symbol NAT10.
- Organism: Homo sapiens.
- Length: 1025 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, systolic blood pressure and Intellectual disability.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | RNA cytidine acetyltransferase |
|---|---|
| UniProt accession | Q9H0A0 |
| Gene | NAT10 |
| Organism | Homo sapiens |
| Length | 1025 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (159)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.46
- systolic blood pressure · score 0.13
- Intellectual disability · score 0.12
- neoplasm · score 0.11
- cancer · score 0.11
- hepatocellular carcinoma · score 0.11
- head and neck squamous cell carcinoma · score 0.10
- endometrial cancer · score 0.10
- Miyoshi myopathy · score 0.09
- lean body mass · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H0A0-F1 | alphafold | PREDICTED | 78.42 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H0A0.
Amino-acid sequence (1025 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NAT10?
The strongest Open Targets associations for NAT10 are neurodegenerative disease, systolic blood pressure, Intellectual disability, neoplasm and cancer.
How long is the NAT10 protein?
The Homo sapiens NAT10 protein (UniProt Q9H0A0) is 1025 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H0A0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H0A0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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