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RING finger protein 32 (RNF32)

Homo sapiens — UniProt Q9H0A6

Gene: RNF32Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

RING finger protein 32 (RNF32) is a protein from Homo sapiens identified by UniProt accession Q9H0A6, 362 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.

  • UniProt accession: Q9H0A6; gene symbol RNF32.
  • Organism: Homo sapiens.
  • Length: 362 amino acids.
  • Top disease associations (Open Targets): cystatin C measurement, urate measurement and triphalangeal thumb-polysyndactyly syndrome.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameRING finger protein 32
UniProt accessionQ9H0A6
GeneRNF32
OrganismHomo sapiens
Length362 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (44)

Diseases linked to this target (Open Targets).

  • cystatin C measurement · score 0.37
  • urate measurement · score 0.36
  • triphalangeal thumb-polysyndactyly syndrome · score 0.33
  • body height · score 0.32
  • appendicular lean mass · score 0.31
  • creatinine measurement · score 0.30
  • testosterone measurement · score 0.30
  • glomerular filtration rate · score 0.29
  • brain volume measurement · score 0.28
  • heel bone mineral density · score 0.28

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9H0A6-F1alphafoldPREDICTED79.22—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H0A6.

Amino-acid sequence (362 residues)

MLKNKGHSSK KDNLAVNAVA LQDHILHDLQ LRNLSVADHS KTQVQKKENK SLKRDTKAII DTGLKKTTQC PKLEDSEKEY VLDPKPPPLT LAQKLGLIGP PPPPLSSDEW EKVKQRSLLQ GDSVQPCPIC KEEFELRPQV LLSCSHVFHK ACLQAFEKFT NKKTCPLCRK NQYQTRVIHD GARLFRIKCV TRIQAYWRGC VVRKWYRNLR KTVPPTDAKL RKKFFEKKFT EISHRILCSY NTNIEELFAE IDQCLAINRS VLQQLEEKCG HEITEEEWEK IQVQALRRET HECSICLAPL SAAGGQRVGA GRRSREMALL SCSHVFHHAC LLALEEFSVG DRPPFHACPL CRSCYQKKIL EC

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with RNF32?

The strongest Open Targets associations for RNF32 are cystatin C measurement, urate measurement, triphalangeal thumb-polysyndactyly syndrome, body height and appendicular lean mass.

How long is the RNF32 protein?

The Homo sapiens RNF32 protein (UniProt Q9H0A6) is 362 amino acids long.

Browse: Targets: R · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9H0A6
GeneRNF32
OrganismHomo sapiens
Length362
Binders0
Diseases44
View on UniProt