Speriolin-like protein (SPATC1L)
Homo sapiens — UniProt Q9H0A9
Data last refreshed: (UniProt release unknown)
Key facts
Speriolin-like protein (SPATC1L) is a protein from Homo sapiens identified by UniProt accession Q9H0A9, 340 residues long. MolForge cross-references it against 0 known binders and 102 disease associations.
- UniProt accession: Q9H0A9; gene symbol SPATC1L.
- Organism: Homo sapiens.
- Length: 340 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, deafness and viral load.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Speriolin-like protein |
|---|---|
| UniProt accession | Q9H0A9 |
| Gene | SPATC1L |
| Organism | Homo sapiens |
| Length | 340 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (102)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.30
- deafness · score 0.18
- viral load · score 0.13
- azoospermia · score 0.12
- reticulocyte count · score 0.10
- male infertility with teratozoospermia due to single gene mutation · score 0.10
- reticulocyte measurement · score 0.10
- spermatogenic failure 20 · score 0.09
- spermatogenic failure 5 · score 0.09
- spermatogenic failure 72 · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H0A9-F1 | alphafold | PREDICTED | 68.50 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H0A9.
Amino-acid sequence (340 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SPATC1L?
The strongest Open Targets associations for SPATC1L are neurodegenerative disease, deafness, viral load, azoospermia and reticulocyte count.
How long is the SPATC1L protein?
The Homo sapiens SPATC1L protein (UniProt Q9H0A9) is 340 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H0A9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H0A9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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