IQ domain-containing protein N (IQCN)
Homo sapiens — UniProt Q9H0B3
Data last refreshed: (UniProt release unknown)
Key facts
IQ domain-containing protein N (IQCN) is a protein from Homo sapiens identified by UniProt accession Q9H0B3, 1180 residues long. MolForge cross-references it against 0 known binders and 139 disease associations.
- UniProt accession: Q9H0B3; gene symbol IQCN.
- Organism: Homo sapiens.
- Length: 1180 amino acids.
- Top disease associations (Open Targets): BMI-adjusted waist-hip ratio, monocyte count and urate measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | IQ domain-containing protein N |
|---|---|
| UniProt accession | Q9H0B3 |
| Gene | IQCN |
| Organism | Homo sapiens |
| Length | 1180 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (139)
Diseases linked to this target (Open Targets).
- BMI-adjusted waist-hip ratio · score 0.34
- monocyte count · score 0.30
- urate measurement · score 0.28
- waist-hip ratio · score 0.27
- hypothyroidism · score 0.26
- body fat percentage · score 0.26
- smoking behavior · score 0.23
- BMI-adjusted waist circumference · score 0.23
- appendicular lean mass · score 0.22
- lymphocyte count · score 0.22
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H0B3-F1 | alphafold | PREDICTED | 45.67 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H0B3.
Amino-acid sequence (1180 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with IQCN?
The strongest Open Targets associations for IQCN are BMI-adjusted waist-hip ratio, monocyte count, urate measurement, waist-hip ratio and hypothyroidism.
How long is the IQCN protein?
The Homo sapiens IQCN protein (UniProt Q9H0B3) is 1180 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H0B3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H0B3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.