Cysteine-rich secretory protein LCCL domain-containing 2 (CRISPLD2)
Homo sapiens — UniProt Q9H0B8
Data last refreshed: (UniProt release unknown)
Key facts
Cysteine-rich secretory protein LCCL domain-containing 2 (CRISPLD2) is a protein from Homo sapiens identified by UniProt accession Q9H0B8, 497 residues long. MolForge cross-references it against 0 known binders and 116 disease associations.
- UniProt accession: Q9H0B8; gene symbol CRISPLD2.
- Organism: Homo sapiens.
- Length: 497 amino acids.
- Top disease associations (Open Targets): body height, blood protein measurement and Inguinal hernia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cysteine-rich secretory protein LCCL domain-containing 2 |
|---|---|
| UniProt accession | Q9H0B8 |
| Gene | CRISPLD2 |
| Organism | Homo sapiens |
| Length | 497 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (116)
Diseases linked to this target (Open Targets).
- body height · score 0.68
- blood protein measurement · score 0.43
- Inguinal hernia · score 0.40
- appendicular lean mass · score 0.33
- diverticulitis · score 0.33
- Abdominal Aortic Aneurysm · score 0.29
- diverticular disease · score 0.29
- grip strength measurement · score 0.27
- hip circumference · score 0.18
- forced expiratory volume · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H0B8-F1 | alphafold | PREDICTED | 80.67 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H0B8.
Amino-acid sequence (497 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CRISPLD2?
The strongest Open Targets associations for CRISPLD2 are body height, blood protein measurement, Inguinal hernia, appendicular lean mass and diverticulitis.
How long is the CRISPLD2 protein?
The Homo sapiens CRISPLD2 protein (UniProt Q9H0B8) is 497 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H0B8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H0B8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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