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Zinc finger MYND domain-containing protein 12 (ZMYND12)

Homo sapiens — UniProt Q9H0C1

Gene: ZMYND12Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Zinc finger MYND domain-containing protein 12 (ZMYND12) is a protein from Homo sapiens identified by UniProt accession Q9H0C1, 365 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.

  • UniProt accession: Q9H0C1; gene symbol ZMYND12.
  • Organism: Homo sapiens.
  • Length: 365 amino acids.
  • Top disease associations (Open Targets): neurodegenerative disease, pulse pressure measurement and systolic blood pressure.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameZinc finger MYND domain-containing protein 12
UniProt accessionQ9H0C1
GeneZMYND12
OrganismHomo sapiens
Length365 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (22)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.37
  • pulse pressure measurement · score 0.17
  • systolic blood pressure · score 0.15
  • leukocyte count · score 0.12
  • immunodeficiency 69 · score 0.04
  • hemolytic anemia due to erythrocyte adenosine deaminase overproduction · score 0.04
  • dehydrated hereditary stomatocytosis · score 0.03
  • megaloblastic anemia, folate-responsive · score 0.03
  • elliptocytosis 2 · score 0.03
  • Rh deficiency syndrome · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9H0C1-F1alphafoldPREDICTED90.52—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H0C1.

Amino-acid sequence (365 residues)

MNVIYPLAVP KGRRLCCEVC EAPAERVCAA CTVTYYCGVV HQKADWDSIH EKICQLLIPL RTSMPFYNSE EERQHGLQQL QQRQKYLIEF CYTIAQKYLF EGKHEDAVPA ALQSLRFRVK LYGLSSVELV PAYLLLAEAS LGLGRIVQAE EYLFQAQWTV LKSTDCSNAT HSLLHRNLGL LYIAKKNYEE ARYHLANDIY FASCAFGTED IRTSGGYFHL ANIFYDLKKL DLADTLYTKV SEIWHAYLNN HYQVLSQAHI QQMDLLGKLF ENDTGLDEAQ EAEAIRILTS ILNIRESTSD KAPQKTIFVL KILVMFYYLM MNSSKAQEYG MRALSLAKEQ QLDVHEQSTI QELLSLISTE DHPIT

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with ZMYND12?

The strongest Open Targets associations for ZMYND12 are neurodegenerative disease, pulse pressure measurement, systolic blood pressure, leukocyte count and immunodeficiency 69.

How long is the ZMYND12 protein?

The Homo sapiens ZMYND12 protein (UniProt Q9H0C1) is 365 amino acids long.

Browse: Targets: Z · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9H0C1
GeneZMYND12
OrganismHomo sapiens
Length365
Binders0
Diseases22
View on UniProt