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ADP/ATP translocase 4 (SLC25A31)

Homo sapiens — UniProt Q9H0C2

Gene: SLC25A31Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

ADP/ATP translocase 4 (SLC25A31) is a protein from Homo sapiens identified by UniProt accession Q9H0C2, 315 residues long. MolForge cross-references it against 0 known binders and 111 disease associations.

  • UniProt accession: Q9H0C2; gene symbol SLC25A31.
  • Organism: Homo sapiens.
  • Length: 315 amino acids.
  • Top disease associations (Open Targets): mean corpuscular volume, creatinine measurement and vital capacity.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameADP/ATP translocase 4
UniProt accessionQ9H0C2
GeneSLC25A31
OrganismHomo sapiens
Length315 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (111)

Diseases linked to this target (Open Targets).

  • mean corpuscular volume · score 0.16
  • creatinine measurement · score 0.13
  • vital capacity · score 0.13
  • forced expiratory volume · score 0.11
  • mean corpuscular hemoglobin · score 0.10
  • platelet count · score 0.10
  • azoospermia · score 0.09
  • male infertility with teratozoospermia due to single gene mutation · score 0.07
  • partial chromosome Y deletion · score 0.07
  • mammographic density percentage · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9H0C2-F1alphafoldPREDICTED90.18—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H0C2.

Amino-acid sequence (315 residues)

MHREPAKKKA EKRLFDASSF GKDLLAGGVA AAVSKTAVAP IERVKLLLQV QASSKQISPE ARYKGMVDCL VRIPREQGFF SFWRGNLANV IRYFPTQALN FAFKDKYKQL FMSGVNKEKQ FWRWFLANLA SGGAAGATSL CVVYPLDFAR TRLGVDIGKG PEERQFKGLG DCIMKIAKSD GIAGLYQGFG VSVQGIIVYR ASYFGAYDTV KGLLPKPKKT PFLVSFFIAQ VVTTCSGILS YPFDTVRRRM MMQSGEAKRQ YKGTLDCFVK IYQHEGISSF FRGAFSNVLR GTGGALVLVL YDKIKEFFHI DIGGR

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with SLC25A31?

The strongest Open Targets associations for SLC25A31 are mean corpuscular volume, creatinine measurement, vital capacity, forced expiratory volume and mean corpuscular hemoglobin.

How long is the SLC25A31 protein?

The Homo sapiens SLC25A31 protein (UniProt Q9H0C2) is 315 amino acids long.

Browse: Targets: S · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9H0C2
GeneSLC25A31
OrganismHomo sapiens
Length315
Binders0
Diseases111
View on UniProt