BTB/POZ domain-containing protein 1 (BTBD1)
Homo sapiens — UniProt Q9H0C5
Data last refreshed: (UniProt release unknown)
Key facts
BTB/POZ domain-containing protein 1 (BTBD1) is a protein from Homo sapiens identified by UniProt accession Q9H0C5, 482 residues long. MolForge cross-references it against 0 known binders and 36 disease associations.
- UniProt accession: Q9H0C5; gene symbol BTBD1.
- Organism: Homo sapiens.
- Length: 482 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, basophil count and peak expiratory flow.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | BTB/POZ domain-containing protein 1 |
|---|---|
| UniProt accession | Q9H0C5 |
| Gene | BTBD1 |
| Organism | Homo sapiens |
| Length | 482 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (36)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.29
- basophil count · score 0.21
- peak expiratory flow · score 0.19
- glomerular filtration rate · score 0.16
- chronic obstructive pulmonary disease · score 0.14
- platelet crit · score 0.13
- basophil percentage of leukocytes · score 0.09
- protein measurement · score 0.09
- bipolar disorder · score 0.07
- lymphocyte count · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H0C5-F1 | alphafold | PREDICTED | 86.82 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H0C5.
Amino-acid sequence (482 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BTBD1?
The strongest Open Targets associations for BTBD1 are neurodegenerative disease, basophil count, peak expiratory flow, glomerular filtration rate and chronic obstructive pulmonary disease.
How long is the BTBD1 protein?
The Homo sapiens BTBD1 protein (UniProt Q9H0C5) is 482 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H0C5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H0C5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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