Ubiquitin carboxyl-terminal hydrolase 44 (USP44)
Homo sapiens — UniProt Q9H0E7
Data last refreshed: (UniProt release unknown)
Key facts
Ubiquitin carboxyl-terminal hydrolase 44 (USP44) is a protein from Homo sapiens identified by UniProt accession Q9H0E7, 712 residues long. MolForge cross-references it against 0 known binders and 172 disease associations.
- UniProt accession: Q9H0E7; gene symbol USP44.
- Organism: Homo sapiens.
- Length: 712 amino acids.
- Top disease associations (Open Targets): C-reactive protein measurement, serum gamma-glutamyl transferase measurement and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ubiquitin carboxyl-terminal hydrolase 44 |
|---|---|
| UniProt accession | Q9H0E7 |
| Gene | USP44 |
| Organism | Homo sapiens |
| Length | 712 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (172)
Diseases linked to this target (Open Targets).
- C-reactive protein measurement · score 0.37
- serum gamma-glutamyl transferase measurement · score 0.32
- body height · score 0.31
- sex hormone-binding globulin measurement · score 0.26
- breast carcinoma · score 0.23
- type 2 diabetes mellitus · score 0.23
- breast adenocarcinoma · score 0.23
- HER2 Positive Breast Carcinoma · score 0.22
- hepatocellular carcinoma · score 0.21
- non-small cell lung carcinoma · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H0E7-F1 | alphafold | PREDICTED | 71.86 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H0E7.
Amino-acid sequence (712 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with USP44?
The strongest Open Targets associations for USP44 are C-reactive protein measurement, serum gamma-glutamyl transferase measurement, body height, sex hormone-binding globulin measurement and breast carcinoma.
How long is the USP44 protein?
The Homo sapiens USP44 protein (UniProt Q9H0E7) is 712 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H0E7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H0E7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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