Enkurin domain-containing protein 1 (ENKD1)
Homo sapiens — UniProt Q9H0I2
Data last refreshed: (UniProt release unknown)
Key facts
Enkurin domain-containing protein 1 (ENKD1) is a protein from Homo sapiens identified by UniProt accession Q9H0I2, 346 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.
- UniProt accession: Q9H0I2; gene symbol ENKD1.
- Organism: Homo sapiens.
- Length: 346 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, azoospermia and Stargardt disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Enkurin domain-containing protein 1 |
|---|---|
| UniProt accession | Q9H0I2 |
| Gene | ENKD1 |
| Organism | Homo sapiens |
| Length | 346 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (24)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.26
- azoospermia · score 0.04
- Stargardt disease · score 0.04
- spermatogenic failure 51 · score 0.03
- spermatogenic failure 65 · score 0.03
- Autosomal dominant optic atrophy, classic type · score 0.03
- Wolff-Parkinson-White Syndrome · score 0.03
- dilated cardiomyopathy 1I · score 0.03
- familial sick sinus syndrome · score 0.03
- spermatogenic failure 72 · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H0I2-F1 | alphafold | PREDICTED | 76.26 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H0I2.
Amino-acid sequence (346 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ENKD1?
The strongest Open Targets associations for ENKD1 are neurodegenerative disease, azoospermia, Stargardt disease, spermatogenic failure 51 and spermatogenic failure 65.
How long is the ENKD1 protein?
The Homo sapiens ENKD1 protein (UniProt Q9H0I2) is 346 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H0I2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H0I2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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