Cilia- and flagella-associated protein 263 (CFAP263)
Homo sapiens — UniProt Q9H0I3
Data last refreshed: (UniProt release unknown)
Key facts
Cilia- and flagella-associated protein 263 (CFAP263) is a protein from Homo sapiens identified by UniProt accession Q9H0I3, 377 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.
- UniProt accession: Q9H0I3; gene symbol CFAP263.
- Organism: Homo sapiens.
- Length: 377 amino acids.
- Top disease associations (Open Targets): primary biliary cirrhosis, drug use measurement and squamous cell carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cilia- and flagella-associated protein 263 |
|---|---|
| UniProt accession | Q9H0I3 |
| Gene | CFAP263 |
| Organism | Homo sapiens |
| Length | 377 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (20)
Diseases linked to this target (Open Targets).
- primary biliary cirrhosis · score 0.15
- drug use measurement · score 0.03
- squamous cell carcinoma · score 0.02
- colorectal cancer · score 0.02
- nasopharyngeal neoplasm · score 0.01
- large cell medulloblastoma · score 0.01
- chronic interstitial cystitis · score 0.01
- male infertility · score 0.00
- colonic neoplasm · score 0.00
- chronic obstructive pulmonary disease · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H0I3-F1 | alphafold | PREDICTED | 83.20 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H0I3.
Amino-acid sequence (377 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CFAP263?
The strongest Open Targets associations for CFAP263 are primary biliary cirrhosis, drug use measurement, squamous cell carcinoma, colorectal cancer and nasopharyngeal neoplasm.
How long is the CFAP263 protein?
The Homo sapiens CFAP263 protein (UniProt Q9H0I3) is 377 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H0I3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H0I3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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