Radial spoke head protein 6 homolog A (RSPH6A)
Homo sapiens — UniProt Q9H0K4
Data last refreshed: (UniProt release unknown)
Key facts
Radial spoke head protein 6 homolog A (RSPH6A) is a protein from Homo sapiens identified by UniProt accession Q9H0K4, 717 residues long. MolForge cross-references it against 0 known binders and 124 disease associations.
- UniProt accession: Q9H0K4; gene symbol RSPH6A.
- Organism: Homo sapiens.
- Length: 717 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, eosinophil percentage of leukocytes and mean platelet volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Radial spoke head protein 6 homolog A |
|---|---|
| UniProt accession | Q9H0K4 |
| Gene | RSPH6A |
| Organism | Homo sapiens |
| Length | 717 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (124)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.28
- eosinophil percentage of leukocytes · score 0.23
- mean platelet volume · score 0.16
- eosinophil count · score 0.16
- mean corpuscular hemoglobin concentration · score 0.15
- erythrocyte count · score 0.11
- mean corpuscular volume · score 0.11
- azoospermia · score 0.11
- platelet count · score 0.11
- male infertility with teratozoospermia due to single gene mutation · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H0K4-F1 | alphafold | PREDICTED | 68.52 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H0K4.
Amino-acid sequence (717 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RSPH6A?
The strongest Open Targets associations for RSPH6A are neurodegenerative disease, eosinophil percentage of leukocytes, mean platelet volume, eosinophil count and mean corpuscular hemoglobin concentration.
How long is the RSPH6A protein?
The Homo sapiens RSPH6A protein (UniProt Q9H0K4) is 717 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H0K4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H0K4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.