Cleavage stimulation factor subunit 2 tau variant (CSTF2T)
Homo sapiens — UniProt Q9H0L4
Data last refreshed: (UniProt release unknown)
Key facts
Cleavage stimulation factor subunit 2 tau variant (CSTF2T) is a protein from Homo sapiens identified by UniProt accession Q9H0L4, 616 residues long. MolForge cross-references it against 0 known binders and 131 disease associations.
- UniProt accession: Q9H0L4; gene symbol CSTF2T.
- Organism: Homo sapiens.
- Length: 616 amino acids.
- Top disease associations (Open Targets): body height, self reported educational attainment and lean body mass.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cleavage stimulation factor subunit 2 tau variant |
|---|---|
| UniProt accession | Q9H0L4 |
| Gene | CSTF2T |
| Organism | Homo sapiens |
| Length | 616 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (131)
Diseases linked to this target (Open Targets).
- body height · score 0.22
- self reported educational attainment · score 0.18
- lean body mass · score 0.17
- appendicular lean mass · score 0.16
- fat body mass · score 0.16
- sitting height measurement · score 0.15
- body mass index · score 0.13
- bipolar II disorder · score 0.11
- systolic blood pressure · score 0.11
- azoospermia · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H0L4-F1 | alphafold | PREDICTED | 59.05 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H0L4.
Amino-acid sequence (616 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CSTF2T?
The strongest Open Targets associations for CSTF2T are body height, self reported educational attainment, lean body mass, appendicular lean mass and fat body mass.
How long is the CSTF2T protein?
The Homo sapiens CSTF2T protein (UniProt Q9H0L4) is 616 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H0L4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H0L4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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