Pterin-4-alpha-carbinolamine dehydratase 2 (PCBD2)
Homo sapiens — UniProt Q9H0N5
Data last refreshed: (UniProt release unknown)
Key facts
Pterin-4-alpha-carbinolamine dehydratase 2 (PCBD2) is a protein from Homo sapiens identified by UniProt accession Q9H0N5, 130 residues long. MolForge cross-references it against 0 known binders and 39 disease associations.
- UniProt accession: Q9H0N5; gene symbol PCBD2.
- Organism: Homo sapiens.
- Length: 130 amino acids.
- Top disease associations (Open Targets): blood protein measurement, bone density and urate measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Pterin-4-alpha-carbinolamine dehydratase 2 |
|---|---|
| UniProt accession | Q9H0N5 |
| Gene | PCBD2 |
| Organism | Homo sapiens |
| Length | 130 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (39)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.24
- bone density · score 0.22
- urate measurement · score 0.22
- heel bone mineral density · score 0.13
- body height · score 0.11
- eosinophil count · score 0.09
- anthropometric measurement · score 0.08
- BMI-adjusted hip circumference · score 0.06
- forced expiratory volume · score 0.05
- apolipoprotein A 1 measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H0N5-F1 | alphafold | PREDICTED | 86.23 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H0N5.
Amino-acid sequence (130 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PCBD2?
The strongest Open Targets associations for PCBD2 are blood protein measurement, bone density, urate measurement, heel bone mineral density and body height.
How long is the PCBD2 protein?
The Homo sapiens PCBD2 protein (UniProt Q9H0N5) is 130 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H0N5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H0N5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.