Cytosolic 5'-nucleotidase 3A (NT5C3A)
Homo sapiens — UniProt Q9H0P0
Data last refreshed: (UniProt release unknown)
Key facts
Cytosolic 5'-nucleotidase 3A (NT5C3A) is a protein from Homo sapiens identified by UniProt accession Q9H0P0, 336 residues long. MolForge cross-references it against 0 known binders and 79 disease associations.
- UniProt accession: Q9H0P0; gene symbol NT5C3A.
- Organism: Homo sapiens.
- Length: 336 amino acids.
- Top disease associations (Open Targets): hemolytic anemia due to pyrimidine 5' nucleotidase deficiency, Red cell distribution width and creatinine measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cytosolic 5'-nucleotidase 3A |
|---|---|
| UniProt accession | Q9H0P0 |
| Gene | NT5C3A |
| Organism | Homo sapiens |
| Length | 336 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (79)
Diseases linked to this target (Open Targets).
- hemolytic anemia due to pyrimidine 5' nucleotidase deficiency · score 0.80
- Red cell distribution width · score 0.48
- creatinine measurement · score 0.38
- acute myeloid leukemia · score 0.37
- glomerular filtration rate · score 0.36
- reticulocyte measurement · score 0.35
- reticulocyte count · score 0.33
- serum metabolite measurement · score 0.31
- mean corpuscular volume · score 0.31
- mean reticulocyte volume · score 0.31
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H0P0-F1 | alphafold | PREDICTED | 91.82 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H0P0.
Amino-acid sequence (336 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NT5C3A?
The strongest Open Targets associations for NT5C3A are hemolytic anemia due to pyrimidine 5' nucleotidase deficiency, Red cell distribution width, creatinine measurement, acute myeloid leukemia and glomerular filtration rate.
How long is the NT5C3A protein?
The Homo sapiens NT5C3A protein (UniProt Q9H0P0) is 336 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H0P0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H0P0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.