FXYD domain-containing ion transport regulator 6 (FXYD6)
Homo sapiens — UniProt Q9H0Q3
Data last refreshed: (UniProt release unknown)
Key facts
FXYD domain-containing ion transport regulator 6 (FXYD6) is a protein from Homo sapiens identified by UniProt accession Q9H0Q3, 95 residues long. MolForge cross-references it against 0 known binders and 73 disease associations.
- UniProt accession: Q9H0Q3; gene symbol FXYD6.
- Organism: Homo sapiens.
- Length: 95 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, hepatocellular carcinoma and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | FXYD domain-containing ion transport regulator 6 |
|---|---|
| UniProt accession | Q9H0Q3 |
| Gene | FXYD6 |
| Organism | Homo sapiens |
| Length | 95 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (73)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.38
- hepatocellular carcinoma · score 0.09
- neoplasm · score 0.08
- cholangiocarcinoma · score 0.07
- calf circumference measurement · score 0.07
- high density lipoprotein cholesterol measurement · score 0.07
- Monoamine oxidase A deficiency · score 0.06
- Cirrhosis · score 0.05
- glioblastoma multiforme · score 0.05
- DNA methylation · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H0Q3-F1 | alphafold | PREDICTED | 70.22 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H0Q3.
Amino-acid sequence (95 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FXYD6?
The strongest Open Targets associations for FXYD6 are neurodegenerative disease, hepatocellular carcinoma, neoplasm, cholangiocarcinoma and calf circumference measurement.
How long is the FXYD6 protein?
The Homo sapiens FXYD6 protein (UniProt Q9H0Q3) is 95 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H0Q3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H0Q3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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