AP-5 complex subunit mu-1 (AP5M1)
Homo sapiens — UniProt Q9H0R1
Data last refreshed: (UniProt release unknown)
Key facts
AP-5 complex subunit mu-1 (AP5M1) is a protein from Homo sapiens identified by UniProt accession Q9H0R1, 490 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.
- UniProt accession: Q9H0R1; gene symbol AP5M1.
- Organism: Homo sapiens.
- Length: 490 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, adolescent idiopathic scoliosis and genetic disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | AP-5 complex subunit mu-1 |
|---|---|
| UniProt accession | Q9H0R1 |
| Gene | AP5M1 |
| Organism | Homo sapiens |
| Length | 490 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (28)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- adolescent idiopathic scoliosis · score 0.15
- genetic disorder · score 0.12
- monocyte count · score 0.09
- cancer · score 0.08
- glioblastoma multiforme · score 0.07
- neoplasm · score 0.07
- cutaneous mastocytosis · score 0.04
- Mastocytosis · score 0.03
- astrocytoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H0R1-F1 | alphafold | PREDICTED | 86.95 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H0R1.
Amino-acid sequence (490 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with AP5M1?
The strongest Open Targets associations for AP5M1 are neurodegenerative disease, adolescent idiopathic scoliosis, genetic disorder, monocyte count and cancer.
How long is the AP5M1 protein?
The Homo sapiens AP5M1 protein (UniProt Q9H0R1) is 490 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H0R1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H0R1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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