Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial (QRSL1)
Homo sapiens — UniProt Q9H0R6
Data last refreshed: (UniProt release unknown)
Key facts
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial (QRSL1) is a protein from Homo sapiens identified by UniProt accession Q9H0R6, 528 residues long. MolForge cross-references it against 0 known binders and 172 disease associations.
- UniProt accession: Q9H0R6; gene symbol QRSL1.
- Organism: Homo sapiens.
- Length: 528 amino acids.
- Top disease associations (Open Targets): combined oxidative phosphorylation deficiency 40, neurodegenerative disease and blood protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial |
|---|---|
| UniProt accession | Q9H0R6 |
| Gene | QRSL1 |
| Organism | Homo sapiens |
| Length | 528 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (172)
Diseases linked to this target (Open Targets).
- combined oxidative phosphorylation deficiency 40 · score 0.75
- neurodegenerative disease · score 0.46
- blood protein measurement · score 0.26
- gut microbiome measurement · score 0.24
- urate measurement · score 0.24
- hematocrit · score 0.22
- erythrocyte count · score 0.21
- blood urea nitrogen measurement · score 0.21
- hemoglobin measurement · score 0.21
- creatinine measurement · score 0.21
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H0R6-F1 | alphafold | PREDICTED | 93.48 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H0R6.
Amino-acid sequence (528 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with QRSL1?
The strongest Open Targets associations for QRSL1 are combined oxidative phosphorylation deficiency 40, neurodegenerative disease, blood protein measurement, gut microbiome measurement and urate measurement.
How long is the QRSL1 protein?
The Homo sapiens QRSL1 protein (UniProt Q9H0R6) is 528 amino acids long.
Browse: Targets: Q · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H0R6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H0R6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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