Probable ATP-dependent RNA helicase DDX47 (DDX47)
Homo sapiens — UniProt Q9H0S4
Data last refreshed: (UniProt release unknown)
Key facts
Probable ATP-dependent RNA helicase DDX47 (DDX47) is a protein from Homo sapiens identified by UniProt accession Q9H0S4, 455 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.
- UniProt accession: Q9H0S4; gene symbol DDX47.
- Organism: Homo sapiens.
- Length: 455 amino acids.
- Top disease associations (Open Targets): Intellectual disability, endometrial cancer and urate measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Probable ATP-dependent RNA helicase DDX47 |
|---|---|
| UniProt accession | Q9H0S4 |
| Gene | DDX47 |
| Organism | Homo sapiens |
| Length | 455 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (22)
Diseases linked to this target (Open Targets).
- Intellectual disability · score 0.12
- endometrial cancer · score 0.10
- urate measurement · score 0.08
- bone density · score 0.08
- hypertension · score 0.06
- essential hypertension · score 0.05
- mosaic loss of chromosome Y measurement · score 0.04
- calcium measurement · score 0.02
- lung adenocarcinoma · score 0.02
- infection · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H0S4-F1 | alphafold | PREDICTED | 85.63 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H0S4.
Amino-acid sequence (455 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DDX47?
The strongest Open Targets associations for DDX47 are Intellectual disability, endometrial cancer, urate measurement, bone density and hypertension.
How long is the DDX47 protein?
The Homo sapiens DDX47 protein (UniProt Q9H0S4) is 455 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H0S4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H0S4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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