Ras-related protein Rab-17 (RAB17)
Homo sapiens — UniProt Q9H0T7
Data last refreshed: (UniProt release unknown)
Key facts
Ras-related protein Rab-17 (RAB17) is a protein from Homo sapiens identified by UniProt accession Q9H0T7, 212 residues long. MolForge cross-references it against 0 known binders and 49 disease associations.
- UniProt accession: Q9H0T7; gene symbol RAB17.
- Organism: Homo sapiens.
- Length: 212 amino acids.
- Top disease associations (Open Targets): mean platelet volume, non-small cell lung carcinoma and PHF-tau measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ras-related protein Rab-17 |
|---|---|
| UniProt accession | Q9H0T7 |
| Gene | RAB17 |
| Organism | Homo sapiens |
| Length | 212 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (49)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.08
- non-small cell lung carcinoma · score 0.07
- PHF-tau measurement · score 0.05
- refractive error measurement · score 0.05
- hepatocellular carcinoma · score 0.04
- breast cancer · score 0.04
- neoplasm · score 0.03
- heel bone mineral density · score 0.03
- prostate carcinoma · score 0.03
- bone quantitative ultrasound measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H0T7-F1 | alphafold | PREDICTED | 85.23 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H0T7.
Amino-acid sequence (212 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RAB17?
The strongest Open Targets associations for RAB17 are mean platelet volume, non-small cell lung carcinoma, PHF-tau measurement, refractive error measurement and hepatocellular carcinoma.
How long is the RAB17 protein?
The Homo sapiens RAB17 protein (UniProt Q9H0T7) is 212 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H0T7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H0T7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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