Ras-related protein Rab-1B (RAB1B)
Homo sapiens — UniProt Q9H0U4
Data last refreshed: (UniProt release unknown)
Key facts
Ras-related protein Rab-1B (RAB1B) is a protein from Homo sapiens identified by UniProt accession Q9H0U4, 201 residues long. MolForge cross-references it against 0 known binders and 56 disease associations.
- UniProt accession: Q9H0U4; gene symbol RAB1B.
- Organism: Homo sapiens.
- Length: 201 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, alcohol consumption measurement and breast adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ras-related protein Rab-1B |
|---|---|
| UniProt accession | Q9H0U4 |
| Gene | RAB1B |
| Organism | Homo sapiens |
| Length | 201 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (56)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.32
- alcohol consumption measurement · score 0.16
- breast adenocarcinoma · score 0.10
- infect · score 0.07
- infection · score 0.07
- Immature Reticulocyte Fraction Measurement · score 0.06
- lean body mass · score 0.04
- triple-negative breast cancer · score 0.04
- body fat percentage · score 0.04
- fat body mass · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H0U4-F1 | alphafold | PREDICTED | 85.46 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H0U4.
Amino-acid sequence (201 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RAB1B?
The strongest Open Targets associations for RAB1B are neurodegenerative disease, alcohol consumption measurement, breast adenocarcinoma, infect and infection.
How long is the RAB1B protein?
The Homo sapiens RAB1B protein (UniProt Q9H0U4) is 201 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H0U4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H0U4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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