VIP36-like protein (LMAN2L)
Homo sapiens — UniProt Q9H0V9
Data last refreshed: (UniProt release unknown)
Key facts
VIP36-like protein (LMAN2L) is a protein from Homo sapiens identified by UniProt accession Q9H0V9, 348 residues long. MolForge cross-references it against 0 known binders and 33 disease associations.
- UniProt accession: Q9H0V9; gene symbol LMAN2L.
- Organism: Homo sapiens.
- Length: 348 amino acids.
- Top disease associations (Open Targets): autosomal recessive non-syndromic intellectual disability, intellectual disability, autosomal dominant 52 and bipolar disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | VIP36-like protein |
|---|---|
| UniProt accession | Q9H0V9 |
| Gene | LMAN2L |
| Organism | Homo sapiens |
| Length | 348 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (33)
Diseases linked to this target (Open Targets).
- autosomal recessive non-syndromic intellectual disability · score 0.53
- intellectual disability, autosomal dominant 52 · score 0.43
- bipolar disorder · score 0.40
- schizophrenia · score 0.34
- blood protein measurement · score 0.32
- body height · score 0.31
- unipolar depression · score 0.31
- attention deficit hyperactivity disorder · score 0.25
- Tourette syndrome · score 0.25
- obsessive-compulsive disorder · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H0V9-F1 | alphafold | PREDICTED | 84.41 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H0V9.
Amino-acid sequence (348 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LMAN2L?
The strongest Open Targets associations for LMAN2L are autosomal recessive non-syndromic intellectual disability, intellectual disability, autosomal dominant 52, bipolar disorder, schizophrenia and blood protein measurement.
How long is the LMAN2L protein?
The Homo sapiens LMAN2L protein (UniProt Q9H0V9) is 348 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H0V9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H0V9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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